How Dymista^® is used by patients

A product that is easy to use, effective, and works quickly is important for maintaining adherence to therapy, and this in turn has a positive effect on clinical outcomes. Therefore, it is important that patients know the correct method for administering Dymista^®.

1Shake the bottle gently for 5 seconds by tilting it upwards and downwards and then remove the protective cap.

2The first time the nasal spray is used, you must prime the pump:

• Put one finger either side of the spray pump and place your thumb on the bottom of the bottle.
• Press down and release the pump 6 times until a fine mist appears.
• Now your pump is primed and ready to use.
• If the nasal spray has not been used for more than 7 days, you will need to re-prime the pump once by pressing down and releasing the pump.

3Using the spray:

• After blowing your nose, spray once into each nostril keeping the head tilted downward (see video).
• The spray tip should be directed to the outside wall of the nose, using the right hand for the left nostril and the left hand for the right nostril.
• Do not sniff; breathe in gently.
• After use, wipe the spray tip and replace the protective cap.

Watch the video below for a tutorial:

• Derendorf H, et al. Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray. Br J Clin Pharmacol. 2012; 74(1): 125-133.
• Klimek L, et al. Effectiveness of MP29-02 for the treatment of allergic rhinitis in real-life: Results from a noninterventional study. Allergy Asthma Proc. 2015; 36(1): 40-47.
• Dymista^® Summary of Product Characteristics. Available at: https://www.medicines.org.uk/emc/product/9450. Last accessed: November 2023.
• Bousquet J, et al. Onset of Action of the Fixed Combination Intranasal Azelastine-Fluticasone Propionate in an Allergen Exposure Chamber. J Allergy Clin Immunol Pract. 2018; 6(5): 1726-1732.

DYM-2023-0851 November 2023