Suitable for long term use

Dymista® is suitable for long-term use

For perennial allergic rhinitis patients to get the full therapeutic benefit, regular use of treatment is essential. With Dymista®, the duration of treatment should correspond to the period of allergenic exposure and Dymista® is suitable for long-term use'

A 52-week open-label study showed Dymista® has a large therapeutic spectrum, covering not only seasonal allergic rhinitis but also perennial allergic rhinitis with consistent superiority over an intranasal certicostemid2

Fluticasone propionate when delivered in a nasal spray exerts a topical effect without systemic effects due to low systemic bioavailabitlity3

Systemic absorption is negligible with mometasone furoate, fluticasone furcate and fluticasone propionate. Systemic absorption is modest for the remainder, and high for betamethasone which should be used short-term only.

chart

FIGURE: Bioavailability of intranasal corticosteroids. The more recent molecules have little systemic uptake and are suitable for long-term therapy. Adapted from Scudding et al. 20173

Experts Corner

Click below to understand more about Dymista®’s long-term use, discussed by leading Key Opinion Leaders in Allergic Rhinitis

Further Your Understanding

Click on one of the below links to discover more information about Dymista®, including Flow to use Dymista®, guidelines, clinical papers and request materials.

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    Allergic Rhinitis
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    Impact of Rhinitis
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    Onset
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  • Guidelines
    Guidelines
  • Clinical Papers
    Clinical Papers

References

  1. Dymista, Summary of Product Characteristics
  2. Price D et al. A New Therapy (MP29-02) Is Effective for the Long-Term Treatment, Chronic Rhinilis. J Investig Allergol Clin Immunol 2013 Vol. 23(7): 495-503.
  3. Scadding GK, Kariyawasam HH, Scadding G, et al. BSACI guideline for the diagnosis and management of allergic and non-allergic rhinitis (Revised Edition 2017; Frist edition 2007). Clin Exp Allergy. 2017; 47:856-889

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